Homology
This webpage was produced as an assignment for Genetics 564, an undergraduate capstone course at UW-Madison.
Homolog is a word used to describe shared ancestry in structures or genes in different taxa [1]. When it comes to proteins or DNA sequences homology refers to either orthologs or paralogs. Orthologs come about due to a speciation event, and paralogs come from a duplication [1]. Homology is referred to as sequence similarity [1].
Below you will find the homologs for the NF1 protein. The scientific and common name, and a picture of the organism has been provided. Along with a few other helpful tools when looking at homologs. The name of the protein in each organism is provided, along with the accession code that is a link to the NCBI page for the protein. I have also provided the length of the protein in amino acids, and a percent identity to the human isoform of the NF1 protein. A percent identity is the quantitative similarity between sequences, in this case at the amino acid level [2].
Below you will find the homologs for the NF1 protein. The scientific and common name, and a picture of the organism has been provided. Along with a few other helpful tools when looking at homologs. The name of the protein in each organism is provided, along with the accession code that is a link to the NCBI page for the protein. I have also provided the length of the protein in amino acids, and a percent identity to the human isoform of the NF1 protein. A percent identity is the quantitative similarity between sequences, in this case at the amino acid level [2].